GENERATION, ANALYSIS AND FUNCTIONAL ANNOTATION OF EXPRESSED SEQUENCE TAGS FROM THE ECTOPARASITIC MITE PSOROPTES OVIS

Generation, analysis and functional annotation of expressed sequence tags from the ectoparasitic mite Psoroptes ovis

Abstract Background Sheep scab is caused by Psoroptes ovis and is arguably the most important ectoparasitic disease affecting sheep in the UK.The disease is highly contagious and causes and considerable pruritis and irritation and is therefore a major welfare concern.Current methods of treatment are unsustainable and in order to elucidate novel met

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Identification of Key Residues for Enzymatic Carboxylate Reduction

Carboxylate reductases (CARs, E.C.1.2.1.30) generate aldehydes from their corresponding carboxylic acid with high selectivity.Little is known about the structure of CARs and their catalytically important amino acid residues.The identification of key residues for carboxylate reduction provides a starting point to gain deeper understanding of enzymat

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